Role summaryscientist to join lilly immunology discovery's south san francisco team, contributing to preclinical drug discovery efforts for immune-related diseases. You will design, execute and analyze cellular biology experiments addressing key biological questions, and develop medium-to-high throughput assays for evaluating drug candidates. Success requires experience with primary and immortalized cells, proficiency in flow cytometry-based readouts and immunoassays, and the ability to independently run high-quality studies in a collaborative, fast-paced environment.responsibilitiesdesign, execute, and troubleshoot in vitro cellular biology experiments to investigate disease biology and study mechanism of action of drug candidates, including flow cytometry, luminescence/fluorescence assays and immunoassays (e.g. Elisa).develop medium-to-high throughput cellular and whole blood assays for evaluating small molecule inhibitors.purify pbmcs and primary immune cells from human blood and maintain primary and immortalized cell cultures.maintain accurate, organized records of experimental data and protocols in electronic lab notebooks.analyze, interpret and clearly communicate experimental findings and recommendations to project leads and cross-functional project teams.qualificationsrequired: bachelor's degree in cell biology, immunology or a closely related scientific field.required: 3+ years of laboratory research experience, preferably in industry settings.preferred: working knowledge of cell biology concepts and understanding of assay principles.preferred: hands-on experience with cell lines, whole blood and isolation/culture of primary immune cells (from human blood).preferred: experience with immunoassays (elisa/msd/htrf), multi-color flow cytometry (staining, acquisition, analysis using flowjo) and protein detection (e.g. Western blotting).preferred: experience with cellular and biochemical assays in 96- and 384-well format.preferred: research experience working with small molecules, as well as experience with qpcr and crispr, would be advantageous.preferred: proven ability to work both independently and collaboratively within a research team.preferred: excellent communication, time management, and record-keeping skills.preferred: data analysis using graphpad prism and excel.skillscell biology concepts and assay principle understandingflow cytometry (staining, acquisition, analysis)immunoassays (elisa, msd, htrf)protein detection (e.g., western blotting)cell line and primary immune cell culture96- and 384-well format assay developmentqpcr and crispr experience (advantageous)independent and collaborative work stylestrong communication and data analysis (graphpad prism, excel)educationbachelor\'s degree in cell biology, immunology or a closely related scientific field
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